Preferred Name |
Recombinant Interleukin |
|
Synonyms |
|
|
Definitions |
Formulated therapeutic analogs of one of a number of endogenous cytokine interleukins. Produced by T cells, macrophages, and other cells, interleukins bind to a specific surface receptor on immunohematopoietic cells, thereby inducing a multitude of biologic effects including stimulation of growth, differentiation, and proliferation of lymphocytes and eosinophils; activation of lymphocytes and macrophages; enhancement of mast cell activity; activation of the acute phase response; and stimulation of hematopoiesis. Some interleukins may enhance the host's immune response to malignant cells by stimulating lymphokine-activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL), which are capable of lysing some tumor cells. (NCI04) |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C593 |
|
code |
C593 |
|
definition |
Formulated therapeutic analogs of one of a number of endogenous cytokine interleukins. Produced by T cells, macrophages, and other cells, interleukins bind to a specific surface receptor on immunohematopoietic cells, thereby inducing a multitude of biologic effects including stimulation of growth, differentiation, and proliferation of lymphocytes and eosinophils; activation of lymphocytes and macrophages; enhancement of mast cell activity; activation of the acute phase response; and stimulation of hematopoiesis. Some interleukins may enhance the host's immune response to malignant cells by stimulating lymphokine-activated killer (LAK) cells and tumor-infiltrating lymphocytes (TIL), which are capable of lysing some tumor cells. (NCI04) |
|
label |
Recombinant Interleukin |
|
Legacy Concept Name |
Therapeutic_Interleukin |
|
Preferred_Name |
Recombinant Interleukin |
|
prefixIRI |
NCIT:C593 |
|
prefLabel |
Recombinant Interleukin |
|
Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
|
UMLS_CUI |
C1527200 |
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subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C593 | NCIT | LOOM |