Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C589
http://purl.obolibrary.org/obo/NCIT_C589
Preferred Name

Binetrakin
Definitions
A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B-cells and enhancing their ability to present antigens to T-cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B-cells and enhancing their ability to present antigens to T-cells. As a potential immunotherapeutic agent, binetrakin also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).
prefLabel
Binetrakin
label
Binetrakin
PDQ_Closed_Trial_Search_ID
39324
code
C589
prefixIRI
NCIT:C589
in_subset
Preferred_Name
Binetrakin
FDA_UNII_Code
751635Z921
Contributing_Source
FDA
Maps_To
Binetrakin
CAS_Registry
207137-56-2
NSC Number
618085
620211
NCI_Drug_Dictionary_ID
39324
Legacy Concept Name
Therapeutic_Interleukin-4
type
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
39324
Semantic_Type
Amino Acid, Peptide, or Protein
Pharmacologic Substance
Immunologic Factor
UMLS_CUI
C1522540
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