Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C555
http://purl.obolibrary.org/obo/NCIT_C555
Preferred Name

Therapeutic Hydrocortisone
Definitions
A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04)
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A synthetic or semisynthetic analog of natural hydrocortisone hormone produced by the adrenal glands with primary glucocorticoid and minor mineralocorticoid effects. As a glucocorticoid receptor agonist, hydrocortisone promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory responses. (NCI04)
prefLabel
Therapeutic Hydrocortisone
label
Therapeutic Hydrocortisone
CHEBI_ID
CHEBI:17650
PDQ_Closed_Trial_Search_ID
39274
code
C555
Has_Target
prefixIRI
NCIT:C555
in_subset
Display_Name
Therapeutic Hydrocortisone
Preferred_Name
Therapeutic Hydrocortisone
FDA_UNII_Code
WI4X0X7BPJ
Contributing_Source
CTRP
FDA
Chemical_Formula
C21H30O5
Maps_To
Therapeutic Hydrocortisone
CAS_Registry
50-23-7
NSC Number
10482
10483
NCI_Drug_Dictionary_ID
39274
Legacy Concept Name
Therapeutic_Hydrocortisone
type
ALT_DEFINITION
A drug used to relieve the symptoms of certain hormone shortages and to suppress an immune response.
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
39274
Semantic_Type
Organic Chemical
Pharmacologic Substance
UMLS_CUI
C0020268
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