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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C53412
http://purl.obolibrary.org/obo/NCIT_C53412
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|---|---|
| Preferred Name | Rose Bengal Solution PV-10 |
| Definitions |
An injectable ten percent solution of rose bengal disodium, an iodinated fluorescein derivative, with potential antineoplastic and radiosensitizing activities. When injected into tumor tissue, PV-10 specifically targets and concentrates in tumor cells, producing cytotoxic singlet oxygen when exposed to ionizing radiation. In addition, PV-10 may stimulate an anti-tumor immune response.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An injectable ten percent solution of rose bengal disodium, an iodinated fluorescein derivative, with potential antineoplastic and radiosensitizing activities. When injected into tumor tissue, PV-10 specifically targets and concentrates in tumor cells, producing cytotoxic singlet oxygen when exposed to ionizing radiation. In addition, PV-10 may stimulate an anti-tumor immune response. |
|---|---|
| prefLabel | Rose Bengal Solution PV-10
|
| label | Rose Bengal Solution PV-10
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| PDQ_Closed_Trial_Search_ID | 463937
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| code | C53412
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| prefixIRI | NCIT:C53412
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| in_subset |
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| Display_Name | PV-10
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| Preferred_Name | Rose Bengal Solution PV-10
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| Contributing_Source | CTRP
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| Maps_To |
Rose Bengal Solution PV-10
PV-10
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| NCI_Drug_Dictionary_ID | 463937
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| Legacy Concept Name | PV-10
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 463937
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C1709443
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