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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C53396
http://purl.obolibrary.org/obo/NCIT_C53396
|
|---|---|
| Preferred Name | Cytokine-based Biologic Agent IRX-2 |
| Definitions |
A cell-free mixture comprised of a variety of naturally-derived cytokines obtained from normal, unrelated donor lymphocytes with potential immunostimulatory activity. The cytokines in IRX-2, including interleukin (IL)-1, -2, -6, -8, -10, -12, tumor necrosis factor alpha (TNF-a), interferon-gamma (IFN-g) and colony stimulating factors (CSFs), play vital roles in regulating cellular immunity and may synergistically stimulate a cellular immune response against tumor cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cell-free mixture comprised of a variety of naturally-derived cytokines obtained from normal, unrelated donor lymphocytes with potential immunostimulatory activity. The cytokines in IRX-2, including interleukin (IL)-1, -2, -6, -8, -10, -12, tumor necrosis factor alpha (TNF-a), interferon-gamma (IFN-g) and colony stimulating factors (CSFs), play vital roles in regulating cellular immunity and may synergistically stimulate a cellular immune response against tumor cells. |
|---|---|
| prefLabel | Cytokine-based Biologic Agent IRX-2
|
| label | Cytokine-based Biologic Agent IRX-2
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| PDQ_Closed_Trial_Search_ID | 462160
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| code | C53396
|
| prefixIRI | NCIT:C53396
|
| in_subset | |
| Preferred_Name | Cytokine-based Biologic Agent IRX-2
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| FDA_UNII_Code | ZDR4QSJ43F
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| Contributing_Source | FDA
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| Maps_To | Cytokine-based Biologic Agent IRX-2
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| CAS_Registry | 951209-71-5
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| NCI_Drug_Dictionary_ID | 462160
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| Legacy Concept Name | IRX-2
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 462160
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C0758290
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| Delete | Subject | Author | Type | Created |
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