Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C52188 http://purl.obolibrary.org/obo/NCIT_C52188
Preferred Name	Etoricoxib
Definitions	A synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
Type	http://www.w3.org/2002/07/owl#Class

definition	A synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.
prefLabel	Etoricoxib
label	Etoricoxib
CHEBI_ID	CHEBI:6339
PDQ_Closed_Trial_Search_ID	462092
code	C52188
prefixIRI	NCIT:C52188
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Etoricoxib
FDA_UNII_Code	WRX4NFY03R
Contributing_Source	FDA
Chemical_Formula	C18H15ClN2O2S
Maps_To	Etoricoxib
CAS_Registry	202409-33-4
NCI_Drug_Dictionary_ID	462092
Legacy Concept Name	Etoricoxib
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C1323
PDQ_Open_Trial_Search_ID	462092
Semantic_Type	Pharmacologic Substance
UMLS_CUI	C0972314

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