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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C52182
http://purl.obolibrary.org/obo/NCIT_C52182
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|---|---|
| Preferred Name | CDK1/2/4 Inhibitor AG-024322 |
| Definitions |
A cyclin-dependent kinase (CDK) inhibitor with antineoplastic activity. AG-024322 selectively inhibits cyclin-dependent kinases (particularly CDK1,2 and 4), enzymes that regulate cell cycle progression. Inhibition of CDK may result in cell cycle arrest, induction of apoptosis, and inhibition of DNA replication and tumor cell proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cyclin-dependent kinase (CDK) inhibitor with antineoplastic activity. AG-024322 selectively inhibits cyclin-dependent kinases (particularly CDK1,2 and 4), enzymes that regulate cell cycle progression. Inhibition of CDK may result in cell cycle arrest, induction of apoptosis, and inhibition of DNA replication and tumor cell proliferation. |
|---|---|
| prefLabel | CDK1/2/4 Inhibitor AG-024322
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| label | CDK1/2/4 Inhibitor AG-024322
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| PDQ_Closed_Trial_Search_ID | 459491
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| code | C52182
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| prefixIRI | NCIT:C52182
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| in_subset | |
| Preferred_Name | CDK1/2/4 Inhibitor AG-024322
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| FDA_UNII_Code | 926F8X7TNO
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| Contributing_Source | FDA
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| Maps_To | CDK1/2/4 Inhibitor AG-024322
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| CAS_Registry | 837364-57-5
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| NCI_Drug_Dictionary_ID | 459491
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| Legacy Concept Name | AG-024322
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 459491
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1706655
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