loading...| Preferred Name |
Oxitriptan |
|
| Synonyms |
|
|
| Definitions |
An aromatic amino acid with antidepressant activity. In vivo, oxitriptan (or 5-hydroxytryptophan) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous oxitriptan is produced from the essential amino acid L-tryptophan. The exogenous therapeutic form is isolated from the seeds of the African plant Griffonia simplicifolia. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C52181 |
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| CAS_Registry |
4350-09-8 |
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| CHEBI_ID |
CHEBI:17780 |
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| Chemical_Formula |
C11H12N2O3 |
|
| code |
C52181 |
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| Contributing_Source |
FDA |
|
| definition |
An aromatic amino acid with antidepressant activity. In vivo, oxitriptan (or 5-hydroxytryptophan) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous oxitriptan is produced from the essential amino acid L-tryptophan. The exogenous therapeutic form is isolated from the seeds of the African plant Griffonia simplicifolia. |
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| FDA_UNII_Code |
C1LJO185Q9 |
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| in_subset | ||
| label |
Oxitriptan |
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| Legacy Concept Name |
_5-Hydroxytryptophan |
|
| NCI_Drug_Dictionary_ID |
459776 |
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| NSC Number |
92523 |
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| PDQ_Closed_Trial_Search_ID |
459776 |
|
| PDQ_Open_Trial_Search_ID |
459776 |
|
| Preferred_Name |
Oxitriptan |
|
| prefixIRI |
NCIT:C52181 |
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| prefLabel |
Oxitriptan |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0000578 |
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| subClassOf |