Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Potassium-Sparing Diuretic
Synonyms
Definitions

Any diuretic agent that produces diuresis without increasing potassium excretion. Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.
ID

http://purl.obolibrary.org/obo/NCIT_C49186
code

C49186
definition

Any diuretic agent that produces diuresis without increasing potassium excretion. Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.
label

Potassium-Sparing Diuretic
Legacy Concept Name

Potassium-Sparing_Diuretic
Preferred_Name

Potassium-Sparing Diuretic
prefixIRI

NCIT:C49186
prefLabel

Potassium-Sparing Diuretic
Semantic_Type

Chemical Viewed Functionally
UMLS_CUI

C3536751
subClassOf

http://purl.obolibrary.org/obo/NCIT_C448
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