Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C49088 http://purl.obolibrary.org/obo/NCIT_C49088
Preferred Name	Bavituximab
Definitions	A chimeric, IgG1 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Bavituximab binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels.
Type	http://www.w3.org/2002/07/owl#Class

definition	A chimeric, IgG1 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Bavituximab binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels.
prefLabel	Bavituximab
label	Bavituximab
PDQ_Closed_Trial_Search_ID	450954
code	C49088
prefixIRI	NCIT:C49088
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Display_Name	Bavituximab
Preferred_Name	Bavituximab
FDA_UNII_Code	Q16CT95N25
Contributing_Source	CTRP FDA
Maps_To	Bavituximab
CAS_Registry	648904-28-3
NCI_Drug_Dictionary_ID	450954
Legacy Concept Name	Chimeric_Anti-Phosphotidylserine_Monoclonal_Antibody
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C20401 http://purl.obolibrary.org/obo/NCIT_C129822
PDQ_Open_Trial_Search_ID	450954
Semantic_Type	Pharmacologic Substance
UMLS_CUI	C1707382

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