Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C48426 http://purl.obolibrary.org/obo/NCIT_C48426
Preferred Name	Volociximab
Definitions	A chimeric monoclonal antibody with potential antineoplastic activity. Volociximab binds to and inhibits the activity of alpha(5)beta(1) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI05)
Type	http://www.w3.org/2002/07/owl#Class

definition	A chimeric monoclonal antibody with potential antineoplastic activity. Volociximab binds to and inhibits the activity of alpha(5)beta(1) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI05)
prefLabel	Volociximab
label	Volociximab
PDQ_Closed_Trial_Search_ID	415313
code	C48426
prefixIRI	NCIT:C48426
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Volociximab
FDA_UNII_Code	496K5Z02NW
Contributing_Source	FDA
Maps_To	Volociximab
CAS_Registry	558480-40-3
NCI_Drug_Dictionary_ID	415313
Legacy Concept Name	Volociximab
type	http://www.w3.org/2002/07/owl#Class
ALT_DEFINITION	A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Volociximab binds to a protein that is found on cells that line some tumor blood vessels. It is a type of angiogenesis inhibitor.
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C20401
PDQ_Open_Trial_Search_ID	415313
Semantic_Type	Pharmacologic Substance
UMLS_CUI	C1541160

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