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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C48424
http://purl.obolibrary.org/obo/NCIT_C48424
|
|---|---|
| Preferred Name | Taxane Analogue TPI 287 |
| Definitions |
A synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis. |
|---|---|
| prefLabel | Taxane Analogue TPI 287
|
| label | Taxane Analogue TPI 287
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| PDQ_Closed_Trial_Search_ID | 438803
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| code | C48424
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| Has_Target | |
| prefixIRI | NCIT:C48424
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| in_subset |
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| Display_Name | Taxane Analogue TPI 287
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| Preferred_Name | Taxane Analogue TPI 287
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| Contributing_Source | CTRP
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| Maps_To | Taxane Analogue TPI 287
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| CAS_Registry | 849213-15-6
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| NCI_Drug_Dictionary_ID | 438803
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| Legacy Concept Name | TPI_287
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 438803
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1710314
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