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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C48416
http://purl.obolibrary.org/obo/NCIT_C48416
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|---|---|
| Preferred Name | Picoplatin |
| Definitions |
A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis. |
|---|---|
| prefLabel | Picoplatin
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| label | Picoplatin
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| PDQ_Closed_Trial_Search_ID | 441243
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| code | C48416
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| Has_Target | |
| prefixIRI | NCIT:C48416
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| in_subset |
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| Display_Name | Picoplatin
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| Preferred_Name | Picoplatin
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| FDA_UNII_Code | B5TAN0L720
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C6H7N.2Cl.Pt.H3N
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| Maps_To | Picoplatin
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| CAS_Registry | 181630-15-9
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| NCI_Drug_Dictionary_ID | 441243
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| Legacy Concept Name | Picoplatin
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| type | |
| ALT_DEFINITION | A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called platinum analogs.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 441243
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| Semantic_Type |
Pharmacologic Substance
Inorganic Chemical
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| UMLS_CUI | C0671135
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