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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C48407
http://purl.obolibrary.org/obo/NCIT_C48407
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|---|---|
| Preferred Name | Monoclonal Antibody HuAFP31 |
| Definitions |
A humanized monoclonal antibody directed against alpha fetoprotein with potential antineoplastic activity. Upon administration, monoclonal antibody HuAFP31 (mAb HuAFP31) binds to and stimulates a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized monoclonal antibody directed against alpha fetoprotein with potential antineoplastic activity. Upon administration, monoclonal antibody HuAFP31 (mAb HuAFP31) binds to and stimulates a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein. |
|---|---|
| prefLabel | Monoclonal Antibody HuAFP31
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| label | Monoclonal Antibody HuAFP31
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| PDQ_Closed_Trial_Search_ID | 425344
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| code | C48407
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| prefixIRI | NCIT:C48407
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| in_subset | |
| Preferred_Name | Monoclonal Antibody HuAFP31
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| Maps_To | Monoclonal Antibody HuAFP31
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| NCI_Drug_Dictionary_ID | 425344
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| Legacy Concept Name | Monoclonal_Antibody_HuAPF31
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| type | |
| ALT_DEFINITION | A monoclonal antibody being studied in the treatment of several types of cancer. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. HuAFP31 attaches to tumor cells that make alpha fetoprotein (AFP). This makes it easier for T cells to find and kill the tumor cells.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 425344
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1541524
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