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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C48397
http://purl.obolibrary.org/obo/NCIT_C48397
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|---|---|
| Preferred Name | Iloprost |
| Definitions |
A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition of platelet aggregation, and decreased tumor cell adhesion to endothelium among other effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory, antineoplastic, and anti-metastatic properties. (NCI05)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A prostacyclin analogue with potential chemopreventive activity. Iloprost binds to the prostacyclin receptor in various target cells, thereby causing vasodilation, inhibition of platelet aggregation, and decreased tumor cell adhesion to endothelium among other effects. Prostacyclin is a naturally occurring eicosanoid with anti-inflammatory, antineoplastic, and anti-metastatic properties. (NCI05) |
|---|---|
| prefLabel | Iloprost
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| label | Iloprost
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| CHEBI_ID | CHEBI:63916
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| PDQ_Closed_Trial_Search_ID | 365679
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| code | C48397
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| prefixIRI | NCIT:C48397
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| in_subset |
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| Preferred_Name | Iloprost
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| FDA_UNII_Code | JED5K35YGL
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| Contributing_Source | FDA
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| Chemical_Formula | C22H32O4
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| Maps_To | Iloprost
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| CAS_Registry | 78919-13-8
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| NCI_Drug_Dictionary_ID | 365679
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| Legacy Concept Name | Iloprost
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| type | |
| ALT_DEFINITION | A substance that is being studied in the prevention of lung cancer. It belongs to the family of drugs called prostaglandin analogs.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 365679
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0079594
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