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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C48380
http://purl.obolibrary.org/obo/NCIT_C48380
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|---|---|
| Preferred Name | pan-HER Kinase Inhibitor AC480 |
| Definitions |
An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. (NCI05)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. (NCI05) |
|---|---|
| prefLabel | pan-HER Kinase Inhibitor AC480
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| label | pan-HER Kinase Inhibitor AC480
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| PDQ_Closed_Trial_Search_ID | 655952
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| code | C48380
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| Has_Target | |
| prefixIRI | NCIT:C48380
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| in_subset |
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| Display_Name | pan-HER Kinase Inhibitor AC480
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| Preferred_Name | pan-HER Kinase Inhibitor AC480
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| FDA_UNII_Code | 2252724U5N
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| Contributing_Source |
CTRP
FDA
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| Maps_To | pan-HER Kinase Inhibitor AC480
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| CAS_Registry | 714971-09-2
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| NCI_Drug_Dictionary_ID | 655952
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| Legacy Concept Name | BMS-599626
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| type | |
| ALT_DEFINITION | A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called protein tyrosine kinase inhibitors.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 655952
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1541473
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