Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C47999
http://purl.obolibrary.org/obo/NCIT_C47999
|
|---|---|
| Preferred Name | Indomethacin Sodium |
| Definitions |
The sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction. |
|---|---|
| prefLabel | Indomethacin Sodium
|
| label | Indomethacin Sodium
|
| code | C47999
|
| prefixIRI | NCIT:C47999
|
| in_subset | |
| Preferred_Name | Indomethacin Sodium
|
| FDA_UNII_Code | 0IMX38M2GG
|
| Contributing_Source | FDA
|
| Chemical_Formula | C19H15ClNO4.Na.3H2O
|
| CAS_Registry | 74252-25-8
|
| Legacy Concept Name | Indomethacin_Sodium
|
| Has_Free_Acid_Or_Base_Form | |
| type | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
|
| UMLS_CUI | C0982211
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |