Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Demeclocycline
Synonyms
Definitions

A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis.
ID

http://purl.obolibrary.org/obo/NCIT_C47980
CAS_Registry

127-33-3
CHEBI_ID

CHEBI:4392
Chemical_Formula

C21H21ClN2O8
code

C47980
Contributing_Source

FDA
definition

A semi-synthetic, broad-spectrum naphthacene antibiotic produced by the bacterium Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. Demeclocycline also inhibits the effect of vasopressin on the renal tubules, thereby causing diuresis.
FDA_UNII_Code

5R5W9ICI6O
Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C28975
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

Demeclocycline
Legacy Concept Name

Demeclocycline
Preferred_Name

Demeclocycline
prefixIRI

NCIT:C47980
prefLabel

Demeclocycline
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C0011276
subClassOf

http://purl.obolibrary.org/obo/NCIT_C1595
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http://purl.bioontology.org/ontology/SNMI/C-55010 SNMI LOOM
http://purl.bioontology.org/ontology/VANDF/4019707 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003707 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002291 LOINC LOOM
http://stirdf.jst.go.jp/id/200907048570866373 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3686 OCHV LOOM
http://purl.bioontology.org/ontology/RCD/x01IG RCD LOOM
http://purl.bioontology.org/ontology/ATC/D06AA01 ATC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47980 NCIT LOOM
http://www.co-ode.org/ontologies/galen#Demeclocycline GALEN LOOM
http://purl.bioontology.org/ontology/LNC/LP14988-7 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147799 NDFRT LOOM
http://bmi.utah.edu/ontologies/hfontology/C0011276 HFO LOOM
http://purl.obolibrary.org/obo/ARO_3000667 ARO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.562.900.185 RH-MESH LOOM
http://purl.bioontology.org/ontology/MESH/D003707 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/3154 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/J01AA01 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.562.900.185 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00618 MDM LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016918 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_4392 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4392 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_4392 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_4392 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_4392 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4392 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4392 DRON LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0011276 OCHV LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372779007 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906045878002423 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0004986 OMIT LOOM