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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Tubocurarine Chloride | |
| Synonyms |
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| Definitions |
The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated from the bark and stem of Chondodendron tomentosum with a muscle relaxant property. Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This may lead to skeletal muscle relaxation and paralysis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47777 |
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| CAS_Registry |
6989-98-6
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| Chemical_Formula |
C37H41N2O6.Cl.HCl.5H2O
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| code |
C47777
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| Contributing_Source |
FDA
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| definition |
The chloride salt form of tubocurarine, a naturally occurring curare alkaloid isolated from the bark and stem of Chondodendron tomentosum with a muscle relaxant property. Tubocurarine chloride competes with acetylcholine for the nicotinic receptors at the neuromuscular junction of skeletal muscles, thereby inhibiting the action of acetylcholine and blocking the neural transmission without depolarizing the postsynaptic membrane. This may lead to skeletal muscle relaxation and paralysis.
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| FDA_UNII_Code |
900961Z8VR
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| in_subset | ||
| label |
Tubocurarine Chloride
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| Legacy Concept Name |
Tubocurarine_Chloride
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| NSC Number |
36387
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| Preferred_Name |
Tubocurarine Chloride
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| prefixIRI |
NCIT:C47777
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| prefLabel |
Tubocurarine Chloride
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C0282372
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| subClassOf |
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