Preferred Name

Doxapram Hydrochloride

Synonyms
Definitions

A peripheral and central respiratory stimulant with a brief duration of action. Doxapram hydrochloride stimulates respiration by an action on chemoreceptors in the carotid arteries and, at increased dosage, stimulates central respiratory centers in the medulla as well as other parts of the brain and spinal cord. This results in an increased tidal volume and a slightly increased respiratory rate. Doxapram hydrochloride may also improve cardiac output probably due to an increased release of catecholamines. This respiratory stimulant is used in postanesthesia respiratory depression.

ID

http://purl.obolibrary.org/obo/NCIT_C47500

CAS_Registry

7081-53-0

CHEBI_ID

CHEBI:31520

Chemical_Formula

C24H30N2O2.HCl.H2O

code

C47500

Contributing_Source

FDA

definition

A peripheral and central respiratory stimulant with a brief duration of action. Doxapram hydrochloride stimulates respiration by an action on chemoreceptors in the carotid arteries and, at increased dosage, stimulates central respiratory centers in the medulla as well as other parts of the brain and spinal cord. This results in an increased tidal volume and a slightly increased respiratory rate. Doxapram hydrochloride may also improve cardiac output probably due to an increased release of catecholamines. This respiratory stimulant is used in postanesthesia respiratory depression.

FDA_UNII_Code

P5RU6UOQ5Y

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C61736

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Doxapram Hydrochloride

Legacy Concept Name

Doxapram_Hydrochloride

NSC Number

170958

Preferred_Name

Doxapram Hydrochloride

prefixIRI

NCIT:C47500

prefLabel

Doxapram Hydrochloride

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0282152

subClassOf

http://purl.obolibrary.org/obo/NCIT_C47795

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