Preferred Name | Ceforanide | |
Synonyms |
|
|
Definitions |
A semi-synthetic, broad-spectrum, beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. This results in a reduction of cell wall stability and causes cell lysis. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C47436 |
|
CAS_Registry |
60925-61-3 |
|
CHEBI_ID |
CHEBI:3495 |
|
Chemical_Formula |
C20H21N7O6S2 |
|
code |
C47436 |
|
Contributing_Source |
FDA |
|
definition |
A semi-synthetic, broad-spectrum, beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Ceforanide causes inhibition of bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. This results in a reduction of cell wall stability and causes cell lysis. |
|
FDA_UNII_Code |
8M1YF8951V |
|
in_subset | ||
label |
Ceforanide |
|
Legacy Concept Name |
Ceforanide |
|
Preferred_Name |
Ceforanide |
|
prefixIRI |
NCIT:C47436 |
|
prefLabel |
Ceforanide |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0055008 |
|
subClassOf |