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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C44168
http://purl.obolibrary.org/obo/NCIT_C44168
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|---|---|
| Preferred Name | N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl) Urea |
| Definitions |
An orally available isoxazole urea with potential anti-tumor activity. In preclinical trials, N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl)urea inhibited raf kinase, an enzyme capable of reversing the phenotype of ras-transformed cells and blocking tumor growth. (NCI)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally available isoxazole urea with potential anti-tumor activity. In preclinical trials, N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl)urea inhibited raf kinase, an enzyme capable of reversing the phenotype of ras-transformed cells and blocking tumor growth. (NCI) |
|---|---|
| label | N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl) Urea
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| prefLabel | N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl) Urea
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| Legacy Concept Name | N-_5-tert-butyl-3-isoxazolyl_-N-_4-_4-pyridinyl_oxyphenyl_-Urea
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| in_subset | |
| Preferred_Name | N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl) Urea
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| Is_Value_For_GDC_Property | |
| Maps_To | N-(5-tert-butyl-3-isoxazolyl)-N-(4-(4-pyridinyl)oxyphenyl) Urea
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| UMLS_CUI | C1517613
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| prefixIRI | NCIT:C44168
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| subClassOf | |
| code | C44168
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| type | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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