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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Dianhydrogalactitol | |
| Synonyms |
|
|
| Definitions |
A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C425 |
|
| CAS_Registry |
23261-20-3
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|
| code |
C425
|
|
| Contributing_Source |
CTRP FDA
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|
| definition |
A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. (NCI04)
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|
| Display_Name |
Bi-functional Alkylating Agent VAL-083
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|
| FDA_UNII_Code |
4S465RYF7M
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|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
|
| Is_Value_For_GDC_Property | ||
| label |
Dianhydrogalactitol
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|
| Legacy Concept Name |
Dianhydrogalactitol
|
|
| Maps_To |
Dianhydrogalactitol Bi-functional Alkylating Agent VAL-083
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|
| NCI_Drug_Dictionary_ID |
39215 718929
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|
| NSC Number |
132313
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|
| PDQ_Closed_Trial_Search_ID |
39215
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|
| PDQ_Open_Trial_Search_ID |
39215
|
|
| Preferred_Name |
Dianhydrogalactitol
|
|
| prefixIRI |
NCIT:C425
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|
| prefLabel |
Dianhydrogalactitol
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0011967
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| subClassOf |
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