Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C425 http://purl.obolibrary.org/obo/NCIT_C425
Preferred Name	Dianhydrogalactitol
Definitions	A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. (NCI04)
Type	http://www.w3.org/2002/07/owl#Class

definition	A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. (NCI04)
prefLabel	Dianhydrogalactitol
label	Dianhydrogalactitol
PDQ_Closed_Trial_Search_ID	39215
code	C425
prefixIRI	NCIT:C425
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Display_Name	Bi-functional Alkylating Agent VAL-083
Preferred_Name	Dianhydrogalactitol
FDA_UNII_Code	4S465RYF7M
Contributing_Source	CTRP FDA
Maps_To	Dianhydrogalactitol Bi-functional Alkylating Agent VAL-083
CAS_Registry	23261-20-3
NSC Number	132313
NCI_Drug_Dictionary_ID	39215 718929
Legacy Concept Name	Dianhydrogalactitol
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C475
PDQ_Open_Trial_Search_ID	39215
Semantic_Type	Organic Chemical Pharmacologic Substance
UMLS_CUI	C0011967

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