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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C419
http://purl.obolibrary.org/obo/NCIT_C419
|
|---|---|
| Preferred Name | Demecolcine |
| Definitions |
A colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin, inhibiting its polymerization into microtubules, causing cell cycle arrest at metaphase and preventing cell division.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin, inhibiting its polymerization into microtubules, causing cell cycle arrest at metaphase and preventing cell division. |
|---|---|
| prefLabel | Demecolcine
|
| label | Demecolcine
|
| CHEBI_ID | CHEBI:4393
|
| code | C419
|
| prefixIRI | NCIT:C419
|
| in_subset | |
| Preferred_Name | Demecolcine
|
| FDA_UNII_Code | Z01IVE25KI
|
| Contributing_Source | FDA
|
| Chemical_Formula | C21H25NO5
|
| Maps_To | Demecolcine
|
| CAS_Registry | 477-30-5
|
| NSC Number |
3096
403147
|
| Legacy Concept Name | Demecolcine
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0011259
|
| Delete | Subject | Author | Type | Created |
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