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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C417
http://purl.obolibrary.org/obo/NCIT_C417
|
|---|---|
| Preferred Name | Deferoxamine Mesylate |
| Definitions |
The mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and ferrioxamine, a water-soluble complex excreted by the kidneys and in the feces via the bile. This agent does not readily chelate iron bound to transferrin, hemoglobin, myoglobin or cytochrome.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and ferrioxamine, a water-soluble complex excreted by the kidneys and in the feces via the bile. This agent does not readily chelate iron bound to transferrin, hemoglobin, myoglobin or cytochrome. |
|---|---|
| prefLabel | Deferoxamine Mesylate
|
| label | Deferoxamine Mesylate
|
| CHEBI_ID | CHEBI:31460
|
| PDQ_Closed_Trial_Search_ID | 41696
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| code | C417
|
| Has_Target | |
| prefixIRI | NCIT:C417
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| in_subset |
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| Display_Name | Deferoxamine Mesylate
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| Preferred_Name | Deferoxamine Mesylate
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| FDA_UNII_Code | V9TKO7EO6K
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C25H48N6O8.CH4O3S
|
| Maps_To | Deferoxamine Mesylate
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| CAS_Registry | 138-14-7
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| NSC Number | 644468
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| NCI_Drug_Dictionary_ID | 41696
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| Legacy Concept Name | Deferoxamine_Mesylate
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 41696
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0011148
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