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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C407
http://purl.obolibrary.org/obo/NCIT_C407
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|---|---|
| Preferred Name | Cyproterone |
| Definitions |
A synthetic steroidal anti-androgen with antineoplastic activity. Cyproterone, in its acetate form, binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progesterogenic activity, resulting in a reduction in testicular androgen secretion and total androgen blockade. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic steroidal anti-androgen with antineoplastic activity. Cyproterone, in its acetate form, binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progesterogenic activity, resulting in a reduction in testicular androgen secretion and total androgen blockade. (NCI04) |
|---|---|
| prefLabel | Cyproterone
|
| label | Cyproterone
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| Has_Salt_Form | |
| CHEBI_ID | CHEBI:50742
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| code | C407
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| prefixIRI | NCIT:C407
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| in_subset | |
| Preferred_Name | Cyproterone
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| FDA_UNII_Code | E61Q31EK2F
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| Contributing_Source | FDA
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| Chemical_Formula | C22H27ClO3
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| Maps_To | Cyproterone
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| CAS_Registry | 2098-66-0
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| Legacy Concept Name | Cyproterone
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0010621
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