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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C39275
http://purl.obolibrary.org/obo/NCIT_C39275
|
|---|---|
| Preferred Name | Interleukin-3 Receptor Subunit Alpha |
| Definitions |
Interleukin-3 receptor subunit alpha (378 aa, ~43 kDa) is encoded by the human IL3RA gene. This protein is involved in interleukin-3 signaling.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Interleukin-3 receptor subunit alpha (378 aa, ~43 kDa) is encoded by the human IL3RA gene. This protein is involved in interleukin-3 signaling. |
|---|---|
| label | Interleukin-3 Receptor Subunit Alpha
|
| prefLabel | Interleukin-3 Receptor Subunit Alpha
|
| Legacy Concept Name | Interleukin-3_Receptor_Alpha
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| in_subset | |
| Preferred_Name | Interleukin-3 Receptor Subunit Alpha
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| Display_Name | Interleukin-3 Receptor Subunit Alpha
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| Swiss_Prot | P26951
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| DesignNote | Interleukin-3 receptor subunit alpha is a type I membrane protein with a box 1 motif for JAK interaction/activation; a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding. It is also the ligand-binding alpha subunit of the heterodimeric cytokine receptor for interleukin-3 (IL3). Receptor binding to IL3 depends on the cytokine receptor common subunit beta, which is shared by IL3-, IL5-, and CSF2/GM-CSF receptors.
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| UMLS_CUI | C0758637
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| prefixIRI | NCIT:C39275
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| Contributing_Source | CTRP
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| subClassOf | |
| code | C39275
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| type | |
| OMIM_Number |
308385
430000
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
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