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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C38953
http://purl.obolibrary.org/obo/NCIT_C38953
|
|---|---|
| Preferred Name | Integrin AlphaV/Beta3 |
| Definitions |
Involved in cell adhesion and signaling, human Integrin-aVBeta3 is composed of type I membrane protein chains Integrin Alpha V (disulfide-linked heavy and light chains) and Integrin Beta 3 that recognize RGD sequences. Multiple heterodimeric alpha/beta combinations result in different integrins. aV/beta-3 is a receptor for cytotactin, fibronectin, laminin, MMP-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin, and von Willebrand factor. (NCI)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Involved in cell adhesion and signaling, human Integrin-aVBeta3 is composed of type I membrane protein chains Integrin Alpha V (disulfide-linked heavy and light chains) and Integrin Beta 3 that recognize RGD sequences. Multiple heterodimeric alpha/beta combinations result in different integrins. aV/beta-3 is a receptor for cytotactin, fibronectin, laminin, MMP-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin, and von Willebrand factor. (NCI) |
|---|---|
| prefLabel | Integrin AlphaV/Beta3
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| label | Integrin AlphaV/Beta3
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| code | C38953
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| prefixIRI | NCIT:C38953
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| in_subset | |
| Display_Name | Integrin AlphaV/Beta3
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| Preferred_Name | Integrin AlphaV/Beta3
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| Contributing_Source | CTRP
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| Legacy Concept Name | Integrin-aVBeta3
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| Related_To_Genetic_Biomarker | |
| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C1138427
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