Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C38896
http://purl.obolibrary.org/obo/NCIT_C38896
|
|---|---|
| Preferred Name | B-Lymphocyte Antigen CD20 |
| Definitions |
B-lymphocyte antigen CD20 (297 aa, ~33 kDa) is encoded by the human MS4A1 gene. This protein plays a role in both the activation and proliferation of B-cells.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | B-lymphocyte antigen CD20 (297 aa, ~33 kDa) is encoded by the human MS4A1 gene. This protein plays a role in both the activation and proliferation of B-cells. |
|---|---|
| prefLabel | B-Lymphocyte Antigen CD20
|
| label | B-Lymphocyte Antigen CD20
|
| code | C38896
|
| prefixIRI | NCIT:C38896
|
| OMIM_Number | 112210
|
| in_subset |
See more
See less
|
| Display_Name | B-Lymphocyte Antigen CD20
|
| Preferred_Name | B-Lymphocyte Antigen CD20
|
| Contributing_Source |
CTRP
GDC
PCDC
|
| Swiss_Prot | P11836
|
| Maps_To |
CD20
FMC-7
|
| Legacy Concept Name | CD20_Antigen
|
| DesignNote | Expressed during B-cell ontogeny (early pre-B-cell to plasma cell) by human CD20 Gene (MS4A Family), 297-aa 33-kDa CD20 Antigen is a phosphorylated cell surface integral membrane protein shown to participate in B-cell proliferation, development, and differentiation into plasma cells. MS4A family proteins share structural similarity, sequence homology, and unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A proteins contain 4 highly conserved transmembrane domains, flanked by N- and C-terminal cytoplasmic regions. CD20 may be involved in regulation of B-cell activation and may be regulated by protein kinases.
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
|
| UMLS_CUI | C0054946
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |