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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C38711
http://purl.obolibrary.org/obo/NCIT_C38711
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|---|---|
| Preferred Name | Selective Estrogen Receptor Modulator CC-8490 |
| Definitions |
A benzopyran with potential antineoplastic activity. CC-8490 acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A benzopyran with potential antineoplastic activity. CC-8490 acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. (NCI04) |
|---|---|
| prefLabel | Selective Estrogen Receptor Modulator CC-8490
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| label | Selective Estrogen Receptor Modulator CC-8490
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| PDQ_Closed_Trial_Search_ID | 346082
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| code | C38711
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| prefixIRI | NCIT:C38711
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| in_subset | |
| Preferred_Name | Selective Estrogen Receptor Modulator CC-8490
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| Maps_To | Selective Estrogen Receptor Modulator CC-8490
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| NCI_Drug_Dictionary_ID | 346082
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| Legacy Concept Name | CC-8490
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| type | |
| ALT_DEFINITION | A substance that is being studied in the treatment of brain cancer. It belongs to the family of drugs called benzopyrans.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 346082
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1328106
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