Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C38139
http://purl.obolibrary.org/obo/NCIT_C38139
|
|---|---|
| Preferred Name | Talampanel |
| Definitions |
A synthetic derivative of dioxolo-benzodiazepine with anti-seizure activity. Talampanel antagonizes the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) subtype of glutamate excitatory amino acid receptors and may inhibit the growth of gliomas by interfering with neurotransmitters involved in brain tumor growth. This agent may also protect against traumatic brain injury.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic derivative of dioxolo-benzodiazepine with anti-seizure activity. Talampanel antagonizes the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) subtype of glutamate excitatory amino acid receptors and may inhibit the growth of gliomas by interfering with neurotransmitters involved in brain tumor growth. This agent may also protect against traumatic brain injury. |
|---|---|
| prefLabel | Talampanel
|
| label | Talampanel
|
| PDQ_Closed_Trial_Search_ID | 315898
|
| code | C38139
|
| prefixIRI | NCIT:C38139
|
| in_subset | |
| Preferred_Name | Talampanel
|
| FDA_UNII_Code | CVS43XG1L5
|
| Contributing_Source | FDA
|
| Chemical_Formula | C19H19N3O3
|
| Maps_To | Talampanel
|
| CAS_Registry | 161832-65-1
|
| NSC Number | 729898
|
| NCI_Drug_Dictionary_ID | 315898
|
| Legacy Concept Name | Talampanel
|
| type | |
| ALT_DEFINITION | A substance that is being studied in the treatment of brain tumors and other brain disorders, such as epilepsy and Parkinson disease. It is a type of AMPA receptor antagonist.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 315898
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0250723
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |