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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C379
http://purl.obolibrary.org/obo/NCIT_C379
|
|---|---|
| Preferred Name | Clomiphene Citrate |
| Definitions |
The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The citrate salt form of clomiphene, a triphenylethylene nonsteroidal ovulatory stimulant evaluated for antineoplastic activity against breast cancer. Clomiphene has both estrogenic and anti-estrogenic activities that compete with estrogen for binding at estrogen receptor sites in target tissues. This agent causes the release of the pituitary gonadotropins follicle stimulating hormone (FSH) and luteinizing hormone (LH), leading to ovulation. (NCI04) |
|---|---|
| label | Clomiphene Citrate
|
| prefLabel | Clomiphene Citrate
|
| Has_Free_Acid_Or_Base_Form | |
| Legacy Concept Name | Clomiphene
|
| in_subset | |
| Preferred_Name | Clomiphene Citrate
|
| Is_Value_For_GDC_Property | |
| Maps_To | Clomiphene Citrate
|
| PDQ_Open_Trial_Search_ID | 39542
|
| UMLS_CUI | C0546859
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| FDA_UNII_Code | 1B8447E7YI
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| prefixIRI | NCIT:C379
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| NCI_Drug_Dictionary_ID | 39542
|
| Contributing_Source | FDA
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| subClassOf | |
| CHEBI_ID | CHEBI:3753
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| code | C379
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| type | |
| NSC Number | 35770
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| PDQ_Closed_Trial_Search_ID | 39542
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| CAS_Registry | 50-41-9
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| Delete | Subject | Author | Type | Created |
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