Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C37447
http://purl.obolibrary.org/obo/NCIT_C37447
|
|---|---|
| Preferred Name | TSP-1 Mimetic ABT-510 |
| Definitions |
A synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascularization; these pro-angiogenic growth factors include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF)), hepatocyte growth factor (HGF), and interleukin 8 (IL-8). (NCI04)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascularization; these pro-angiogenic growth factors include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF)), hepatocyte growth factor (HGF), and interleukin 8 (IL-8). (NCI04) |
|---|---|
| prefLabel | TSP-1 Mimetic ABT-510
|
| label | TSP-1 Mimetic ABT-510
|
| PDQ_Closed_Trial_Search_ID | 350157
|
| code | C37447
|
| Has_Target | |
| prefixIRI | NCIT:C37447
|
| in_subset |
See more
See less
|
| Display_Name | TSP-1 Mimetic ABT-510
|
| Preferred_Name | TSP-1 Mimetic ABT-510
|
| FDA_UNII_Code | CRR8E37XOB
|
| Contributing_Source |
CTRP
FDA
|
| Maps_To | TSP-1 Mimetic ABT-510
|
| CAS_Registry | 251579-55-2
|
| NCI_Drug_Dictionary_ID | 350157
|
| Legacy Concept Name | ABT-510
|
| type | |
| ALT_DEFINITION | A substance being studied in the treatment of cancer. It is a type of angiogenesis inhibitor.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 350157
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
|
| UMLS_CUI | C1704426
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |