Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Preferred Name | Interferon Alpha/Beta Receptor 2 | |
| Synonyms |
|
|
| Definitions |
Interferon alpha/beta receptor 2 (515 aa, ~58 kDa) is encoded by the human IFNAR2 gene. This protein is involved in interferon signaling. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C37278 |
|
| code |
C37278
|
|
| Contributing_Source |
CTRP
|
|
| definition |
Interferon alpha/beta receptor 2 (515 aa, ~58 kDa) is encoded by the human IFNAR2 gene. This protein is involved in interferon signaling.
|
|
| DesignNote |
Interferon alpha/beta receptor 2 is the beta subunit of the interferon alpha receptor complex, a heterodimeric receptor for type I IFNs, alpha and beta, which also includes interferon alpha/beta receptor 1. Binding of alpha and beta IFNs mediate innate immune responses to viral infection and specific interferon inhibition of virus replication, triggers tyrosine phosphorylation of JAK and STAT proteins, and autophosphorylation of and tyrosine phosphorylation by TYK2. IFNAR2 also interacts with RACK1.
|
|
| Display_Name |
Interferon Alpha/Beta Receptor 2
|
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C173381 http://purl.obolibrary.org/obo/NCIT_C177415 http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Interferon Alpha/Beta Receptor 2
|
|
| Legacy Concept Name |
Interferon_Alpha-Beta_Receptor_Beta_Chain
|
|
| OMIM_Number |
602376
|
|
| Preferred_Name |
Interferon Alpha/Beta Receptor 2
|
|
| prefixIRI |
NCIT:C37278
|
|
| prefLabel |
Interferon Alpha/Beta Receptor 2
|
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Receptor
|
|
| Swiss_Prot |
P48551
|
|
| UMLS_CUI |
C1568206
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |
Create mapping