Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C362
http://purl.obolibrary.org/obo/NCIT_C362
|
|---|---|
| Preferred Name | Chlorambucil |
| Definitions |
An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04) |
|---|---|
| prefLabel | Chlorambucil
|
| label | Chlorambucil
|
| CHEBI_ID | CHEBI:28830
|
| PDQ_Closed_Trial_Search_ID | 43113
|
| code | C362
|
| prefixIRI | NCIT:C362
|
| in_subset |
See more
See less
|
| Display_Name | Chlorambucil
|
| Preferred_Name | Chlorambucil
|
| FDA_UNII_Code | 18D0SL7309
|
| Contributing_Source |
CTRP
FDA
|
| Chemical_Formula | C14H19Cl2NO2
|
| Maps_To | Chlorambucil
|
| CAS_Registry | 305-03-3
|
| NSC Number | 3088
|
| NCI_Drug_Dictionary_ID | 43113
|
| Legacy Concept Name | Chlorambucil
|
| type | |
| ALT_DEFINITION | A drug used to treat several types of leukemias and lymphomas. It blocks cell growth by damaging the cell's DNA and may kill cancer cells. It is a type of alkylating agent.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43113
|
| Accepted_Therapeutic_Use_For | chronic lymphocytic leukemia, Hodgkin lymphoma, and certain types of non-Hodgkin lymphoma.
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0008163
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |