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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Id | http://purl.obolibrary.org/obo/NCIT_C35498
http://purl.obolibrary.org/obo/NCIT_C35498
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|---|---|
| Preferred Name | Toxic Shock Syndrome |
| Definitions |
A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria. |
|---|---|
| label |
Toxic Shock Syndrome
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| prefLabel |
Toxic Shock Syndrome
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| database_cross_reference |
IMDRF:E1414
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| Legacy Concept Name |
Toxic_Shock_Syndrome
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| in_subset | |
| Preferred_Name |
Toxic Shock Syndrome
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| FDA_Table |
Patient Code (Appendix B)
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| Maps_To |
Toxic shock syndrome
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| UMLS_CUI |
C0600327
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| prefixIRI |
NCIT:C35498
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| Contributing_Source |
FDA
MedDRA
NICHD
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| subClassOf | |
| code |
C35498
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| type | |
| ALT_DEFINITION |
A rare acute life-threatening systemic bacterial noncontagious illness caused by staphylococcal exotoxins.
Profoundly reduced blood flow that results in impaired tissue perfusion and possible end organ damage resulting from an exotoxin released from certain bacteria, most often Staphylococcus aureus, or Streptococcus pyogenes.
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| Semantic_Type |
Disease or Syndrome
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