loading...| Preferred Name |
Non-Hodgkin Lymphoma |
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| Synonyms |
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| Definitions |
Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C3211 |
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| ALT_DEFINITION |
Any of a large group of cancers of lymphocytes (white blood cells). NHLs can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss. There are many different types of NHL. These types can be divided into aggressive (fast-growing) and indolent (slow-growing) types, and they can be formed from either B-cells or T-cells. B-cell NHLs include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell NHLs include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma. Lymphomas that occur after bone marrow or stem cell transplantation are usually B-cell NHLs. Prognosis and treatment depend on the stage and type of disease. A malignant neoplasm of the lymphatic system that is comprised of abnormal lymphocytes in the absence of Reed-Sternberg cells. |
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| code |
C3211 |
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| Contributing_Source |
Cellosaurus CPTAC CTEP CTRP GDC MedDRA NICHD |
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| definition |
Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage. |
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| Display_Name |
Non-Hodgkin Lymphoma |
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| ICD-O-3_Code |
9591/3 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C138190 http://purl.obolibrary.org/obo/NCIT_C168658 http://purl.obolibrary.org/obo/NCIT_C168656 http://purl.obolibrary.org/obo/NCIT_C168657 http://purl.obolibrary.org/obo/NCIT_C168655 http://purl.obolibrary.org/obo/NCIT_C90259 http://purl.obolibrary.org/obo/NCIT_C158520 http://purl.obolibrary.org/obo/NCIT_C102905 http://purl.obolibrary.org/obo/NCIT_C168662 http://purl.obolibrary.org/obo/NCIT_C168661 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/ncit#oncotree_slim http://purl.obolibrary.org/obo/NCIT_C175325 http://purl.obolibrary.org/obo/NCIT_C103133 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C158035 http://purl.obolibrary.org/obo/NCIT_C158034 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C118464 http://purl.obolibrary.org/obo/NCIT_C126659 http://purl.obolibrary.org/obo/NCIT_C138188 http://purl.obolibrary.org/obo/NCIT_C165258 http://purl.obolibrary.org/obo/NCIT_C118168 |
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| Is_Value_For_GDC_Property | ||
| label |
Non-Hodgkin Lymphoma |
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| Legacy Concept Name |
Non-Hodgkin_s_Lymphoma |
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| Maps_To |
Large cell lymphoma, unspecified site, extranodal and solid organ sites Other specified types of non-Hodgkin lymphoma, lymph nodes of inguinal region and lower limb Large cell lymphoma Other named variants of lymphosarcoma and reticulosarcoma, unspecified site Other specified types of non-Hodgkin lymphoma, intra-abdominal lymph nodes Reticulosarcoma involving lymph nodes of axilla and upper limb Reticulosarcoma Non-Hodgkin lymphoma, unspecified, unspecified site Non-Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck Reticulosarcoma involving lymph nodes of multiple sites Large cell lymphoma involving intra-abdominal lymph nodes Reticulosarcoma, unspecified site, extranodal and solid organ sites Other and unspecified types of non-Hodgkin lymphoma Lymphosarcoma, unspecified site, extranodal and solid organ sites Reticulosarcoma involving intrathoracic lymph nodes Other specified types of non-Hodgkin lymphoma, lymph nodes of head, face, and neck Lymphosarcoma involving lymph nodes of multiple sites Malignant lymphoma, non-Hodgkin, NOS Other specified types of non-Hodgkin lymphoma Large cell lymphoma involving lymph nodes of multiple sites Large cell lymphoma involving lymph nodes of inguinal region and lower limb Reticulosarcoma involving lymph nodes of inguinal region and lower limb Lymphosarcoma and reticulosarcoma and other specified malignant tumors of lymphatic tissue Other specified types of non-Hodgkin lymphoma, extranodal and solid organ sites Other specified types of non-Hodgkin lymphoma, unspecified site Other specified types of non-Hodgkin lymphoma, intrathoracic lymph nodes Lymphosarcoma Non-Hodgkin's lymphoma Large cell lymphoma involving intrathoracic lymph nodes Reticulosarcoma involving intra-abdominal lymph nodes Lymphosarcoma involving intrathoracic lymph nodes Other named variants of lymphosarcoma and reticulosarcoma Non-Hodgkin lymphoma, unspecified Non-Hodgkin lymphoma, NOS Other specified types of non-Hodgkin lymphoma, lymph nodes of multiple sites Reticulosarcoma involving lymph nodes of head, face, and neck 9591/3 |
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| Neoplasm_Has_Special_Category | ||
| Neoplastic_Status |
Malignant |
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| Preferred_Name |
Non-Hodgkin Lymphoma |
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| prefixIRI |
NCIT:C3211 |
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| prefLabel |
Non-Hodgkin Lymphoma |
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| Semantic_Type |
Neoplastic Process |
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| UMLS_CUI |
C0024305 |
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| subClassOf |