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Biological and Environmental Research Ontology
| Id | http://purl.obolibrary.org/obo/NCIT_C30136
http://purl.obolibrary.org/obo/NCIT_C30136
|
|---|---|
| Preferred Name | Interferon Alfa-N3 |
| Definitions |
A formulated therapeutic analog of the endogenous alpha interferon containing multiple interferon species with antiviral and antitumor properties. Interferons bind to specific cell-surface receptors, leading to the transcription and translation of genes with an interferon-specific response element, thereby inducing: antiviral effects (the most important being inhibition of viral protein synthesis); antiproliferative effects (including inhibition of cellular growth and alteration of cellular differentiation); anticancer effects (including interference with oncogene expression); and immune-modulating effects (including activation of natural killer cells, alteration of cell surface antigen expression, and augmentation of lymphocyte and macrophage cytotoxicity). (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A formulated therapeutic analog of the endogenous alpha interferon containing multiple interferon species with antiviral and antitumor properties. Interferons bind to specific cell-surface receptors, leading to the transcription and translation of genes with an interferon-specific response element, thereby inducing: antiviral effects (the most important being inhibition of viral protein synthesis); antiproliferative effects (including inhibition of cellular growth and alteration of cellular differentiation); anticancer effects (including interference with oncogene expression); and immune-modulating effects (including activation of natural killer cells, alteration of cell surface antigen expression, and augmentation of lymphocyte and macrophage cytotoxicity). (NCI04) |
|---|---|
| prefLabel | Interferon Alfa-N3
|
| label | Interferon Alfa-N3
|
| code | C30136
|
| prefixIRI | NCIT:C30136
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| in_subset | |
| Preferred_Name | Interferon Alfa-N3
|
| FDA_UNII_Code | 47BPR3V3MP
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| Contributing_Source | FDA
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| Maps_To | Interferon Alfa-N3
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| CAS_Registry | 9008-11-1
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| Legacy Concept Name | Interferon_Alfa-N3
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C1621234
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