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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C30109
http://purl.obolibrary.org/obo/NCIT_C30109
|
|---|---|
| Preferred Name | Toll-Like Receptor 8 |
| Definitions |
Toll-like receptor 8 (1041 aa, ~120 kDa) is encoded by the human TLR8 gene. This protein is involved in the regulation of antimicrobial responses.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Toll-like receptor 8 (1041 aa, ~120 kDa) is encoded by the human TLR8 gene. This protein is involved in the regulation of antimicrobial responses. |
|---|---|
| prefLabel | Toll-Like Receptor 8
|
| label | Toll-Like Receptor 8
|
| code | C30109
|
| prefixIRI | NCIT:C30109
|
| OMIM_Number | 300366
|
| in_subset | |
| Display_Name | Toll-Like Receptor 8
|
| Preferred_Name | Toll-Like Receptor 8
|
| Contributing_Source | CTRP
|
| Swiss_Prot | Q9NR97
|
| Legacy Concept Name | Toll-Like_Receptor-8
|
| DesignNote | Toll-like receptor 8 likely acts via MyD88 (TIR interaction) and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
|
| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
|
| UMLS_CUI | C0962444
|
| Delete | Subject | Author | Type | Created |
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| No notes to display |