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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C30098
http://purl.obolibrary.org/obo/NCIT_C30098
|
|---|---|
| Preferred Name | TGF-Beta Receptor Type-1 |
| Definitions |
TGF-beta receptor type-1 (503 aa, ~56 kDa) is encoded by the human TGFBR1 gene. This protein plays a role in both TGF-beta-dependent signaling and serine/threonine phosphorylation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | TGF-beta receptor type-1 (503 aa, ~56 kDa) is encoded by the human TGFBR1 gene. This protein plays a role in both TGF-beta-dependent signaling and serine/threonine phosphorylation. |
|---|---|
| prefLabel | TGF-Beta Receptor Type-1
|
| label | TGF-Beta Receptor Type-1
|
| code | C30098
|
| prefixIRI | NCIT:C30098
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| OMIM_Number | 190181
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| in_subset | |
| Display_Name | TGF-Beta Receptor Type-1
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| Preferred_Name | TGF-Beta Receptor Type-1
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| Contributing_Source | CTRP
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| Swiss_Prot | P36897
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| Legacy Concept Name | Transforming_Growth_Factor_Beta_Receptor-I
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| DesignNote | There are three TGF-beta receptors, Type I and Type II together form a heterodimeric signaling complex that is essential for the transduction of the anti-proliferative signals of TGF-beta. Type III is a transmembrane proteoglycan with a large extracellular domain and a cytoplasmic domain that lacks an obvious signaling motif.
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
Receptor
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| UMLS_CUI | C1686499
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