Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C29980
http://purl.obolibrary.org/obo/NCIT_C29980
|
|---|---|
| Preferred Name | Smoothened Homolog |
| Definitions |
Smoothened homolog (787 aa, ~86 kDa) is encoded by the human SMO gene. This protein plays a role in the modulation of hedgehog signaling pathways.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Smoothened homolog (787 aa, ~86 kDa) is encoded by the human SMO gene. This protein plays a role in the modulation of hedgehog signaling pathways. |
|---|---|
| prefLabel | Smoothened Homolog
|
| label | Smoothened Homolog
|
| code | C29980
|
| prefixIRI | NCIT:C29980
|
| OMIM_Number | 601500
|
| in_subset | |
| Display_Name | Smoothened Homolog
|
| Preferred_Name | Smoothened Homolog
|
| Contributing_Source | CTRP
|
| Swiss_Prot | Q99835
|
| Legacy Concept Name | Smoothened_Homolog_Protein
|
| DesignNote | Smoothened homolog (SMO) contains one frizzled domain that seems to form a complex with patched homologs (PTCH) to transduce the sonic hedgehog protein (SHH) signal. SHH binding to the PTCH receptor appears to relieve constitutive SMO repression by PTCH and to activate target gene transcription.
|
| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
|
| UMLS_CUI | C1311076
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |