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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C29858
http://purl.obolibrary.org/obo/NCIT_C29858
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|---|---|
| Preferred Name | Triethylenemelamine |
| Definitions |
A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A trisaziridine alkylating agent with antineoplastic and carcinogenic properties. Used to induce cancer in experimental animal models, triethylenemelamine ethylates DNA, resulting in inhibition of DNA replication, unscheduled DNA synthesis, chromosomal aberrations, and sister chromatid exchanges. This agent also exhibits reproductive toxicities. (NCI04) |
|---|---|
| prefLabel | Triethylenemelamine
|
| label | Triethylenemelamine
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| CHEBI_ID | CHEBI:27919
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| code | C29858
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| prefixIRI | NCIT:C29858
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| in_subset | |
| Preferred_Name | Triethylenemelamine
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| FDA_UNII_Code | F7IY6HZG9D
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| Contributing_Source | FDA
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| Chemical_Formula | C9H12N6
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| Maps_To | Triethylenemelamine
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| CAS_Registry | 51-18-3
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| NSC Number | 9706
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| Legacy Concept Name | Triethylenemelamine
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0040975
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