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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C298
http://purl.obolibrary.org/obo/NCIT_C298
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|---|---|
| Preferred Name | BCG Vaccine |
| Definitions |
A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, with non-specific immunoadjuvant and immunotherapeutic activities. Although the mechanism of its anti-tumor activity is unclear, immunization with BCG vaccine likely activates a Th1 cytokine response that includes the induction of interferon. Vaccination with BCG vaccine may be immunoprotective against infection with Mycobacterium tuberculosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, with non-specific immunoadjuvant and immunotherapeutic activities. Although the mechanism of its anti-tumor activity is unclear, immunization with BCG vaccine likely activates a Th1 cytokine response that includes the induction of interferon. Vaccination with BCG vaccine may be immunoprotective against infection with Mycobacterium tuberculosis. |
|---|---|
| prefLabel | BCG Vaccine
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| label | BCG Vaccine
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| PDQ_Closed_Trial_Search_ID | 43028
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| code | C298
|
| prefixIRI | NCIT:C298
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| in_subset |
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| Display_Name | BCG Vaccine
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| Preferred_Name | BCG Vaccine
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| Contributing_Source |
CTRP
NICHD
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| Maps_To | BCG Vaccine
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| NSC Number |
116328
116341
614389
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| NCI_Drug_Dictionary_ID | 43028
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| Legacy Concept Name | BCG_Vaccine
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| type | |
| ALT_DEFINITION | A weakened form of the bacterium Mycobacterium bovis (bacillus Calmette-Guerin) that does not cause disease. BCG is used in a solution to stimulate the immune system in the treatment of bladder cancer and as a vaccine to prevent tuberculosis.
A tuberculosis vaccine containing bacillus Calmette-Guérin, a live attenuated strain of Mycobacterium bovis. There are many different strains of BCG vaccine, all of which were originally derived from one strain, but which now have very different properties.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 43028
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| Accepted_Therapeutic_Use_For |
Immunoadjuvant in Vaccine Therapy
Bladder cancer; Tuberculosis, immunization
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| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
Bacterium
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| UMLS_CUI | C3257574
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