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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C29702
http://purl.obolibrary.org/obo/NCIT_C29702
|
|---|---|
| Preferred Name | Histamine-2 Receptor Antagonist |
| Definitions |
Any agent that competitively binds to and blocks the histamine H2 receptors found in the stomach, heart, uterus, on vascular smooth muscle and in the central nervous system (CNS). Of particular clinical relevance is the blockage of H2 receptors found on the parietal cells of the stomach, which prevents gastric acid secretion.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any agent that competitively binds to and blocks the histamine H2 receptors found in the stomach, heart, uterus, on vascular smooth muscle and in the central nervous system (CNS). Of particular clinical relevance is the blockage of H2 receptors found on the parietal cells of the stomach, which prevents gastric acid secretion. |
|---|---|
| prefLabel | Histamine-2 Receptor Antagonist
|
| label | Histamine-2 Receptor Antagonist
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| CHEBI_ID | CHEBI:37961
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| code | C29702
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| prefixIRI | NCIT:C29702
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| in_subset | |
| Preferred_Name | Histamine-2 Receptor Antagonist
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| Contributing_Source |
GDC
NICHD
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| Maps_To | H2 Blockers
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| Legacy Concept Name | Histamine-2_Receptor_Antagonist
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| type | |
| ALT_DEFINITION | A pharmaceutical agent that blocks the binding of histamine to the type II histamine receptor, and is often used to decrease gastric acid production and to treat urticaria.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C0019593
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