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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C29573
http://purl.obolibrary.org/obo/NCIT_C29573
|
|---|---|
| Preferred Name | HLA Class II Histocompatibility Antigen DRB |
| Definitions |
HLA class II DR beta chain proteins (26-28 kD) form heterodimers with alpha (DRA) chains, both anchored in the membrane. Expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages), alpha/beta heterodimers present peptides derived from extracellular proteins. Hundreds of DRB alleles have been described and typing for these polymorphisms is done for transplantation. (NCI)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | HLA class II DR beta chain proteins (26-28 kD) form heterodimers with alpha (DRA) chains, both anchored in the membrane. Expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages), alpha/beta heterodimers present peptides derived from extracellular proteins. Hundreds of DRB alleles have been described and typing for these polymorphisms is done for transplantation. (NCI) |
|---|---|
| prefLabel | HLA Class II Histocompatibility Antigen DRB
|
| label | HLA Class II Histocompatibility Antigen DRB
|
| code | C29573
|
| prefixIRI | NCIT:C29573
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| in_subset | |
| Display_Name | HLA Class II Histocompatibility Antigen DRB
|
| Preferred_Name | HLA Class II Histocompatibility Antigen DRB
|
| Contributing_Source | CTRP
|
| Legacy Concept Name | HLA_Class-II_Histocompatibility_Antigen-DRB
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C1333901
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