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Biological and Environmental Research Ontology
| Preferred Name | Triptorelin Pamoate | |
| Synonyms |
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| Definitions |
The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C29523 |
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| ALT_DEFINITION |
A drug that is used to treat advanced prostate cancer, and is being studied in the treatment of breast cancer. It belongs to the family of hormonal drugs called gonadotropin-releasing hormone analogs.
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| CAS_Registry |
124508-66-3
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| Chemical_Formula |
C64H82N18O13.C23H16O6
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| code |
C29523
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| Contributing_Source |
CTRP FDA
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| definition |
The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. (NCI04)
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| Display_Name |
Triptorelin Pamoate
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| FDA_UNII_Code |
08AN7WA2G0
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| Has_Free_Acid_Or_Base_Form | ||
| Has_Target | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 http://purl.obolibrary.org/obo/NCIT_C128784 |
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| Is_Value_For_GDC_Property | ||
| label |
Triptorelin Pamoate
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| Legacy Concept Name |
Triptorelin_Pamoate
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| Maps_To |
Triptorelin Pamoate
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| NCI_Drug_Dictionary_ID |
468834
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| NSC Number |
724666
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| PDQ_Closed_Trial_Search_ID |
468834
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| PDQ_Open_Trial_Search_ID |
468834
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| Preferred_Name |
Triptorelin Pamoate
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| prefixIRI |
NCIT:C29523
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| prefLabel |
Triptorelin Pamoate
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| Semantic_Type |
Pharmacologic Substance
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| UMLS_CUI |
C1137102
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| subClassOf |
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