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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C29523
http://purl.obolibrary.org/obo/NCIT_C29523
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|---|---|
| Preferred Name | Triptorelin Pamoate |
| Definitions |
The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The pamoate salt of triptorelin, a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion after prolonged administration. After chronic, continuous administration, a sustained decrease in LH, FSH and testicular and ovarian steroidogenesis is observed. The serum testosterone concentration may fall to levels typically seen in surgically castrated men. (NCI04) |
|---|---|
| prefLabel | Triptorelin Pamoate
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| label | Triptorelin Pamoate
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| PDQ_Closed_Trial_Search_ID | 468834
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| code | C29523
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| Has_Target | |
| prefixIRI | NCIT:C29523
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| in_subset |
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| Display_Name | Triptorelin Pamoate
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| Preferred_Name | Triptorelin Pamoate
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| FDA_UNII_Code | 08AN7WA2G0
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C64H82N18O13.C23H16O6
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| Maps_To | Triptorelin Pamoate
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| CAS_Registry | 124508-66-3
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| NSC Number | 724666
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| NCI_Drug_Dictionary_ID | 468834
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| Legacy Concept Name | Triptorelin_Pamoate
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| ALT_DEFINITION | A drug that is used to treat advanced prostate cancer, and is being studied in the treatment of breast cancer. It belongs to the family of hormonal drugs called gonadotropin-releasing hormone analogs.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 468834
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C1137102
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