Preferred Name | Rifamycin | |
Synonyms |
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Definitions |
A natural antibiotic produced by Streptomyces mediterranei, Rifamycin (Ansamycin Family) is a commonly used antimycobacterial drug that inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis; it blocks RNA-polymerase transcription initiation. Rifamycin has an activity spectrum against Gram-positive and Gram-negative bacteria, but is mainly used against Mycobacterium sp. (especially M. tuberculosis) in association with other agents to overcome resistance. (NCI04) |
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ID |
http://purl.obolibrary.org/obo/NCIT_C29406 |
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Accepted_Therapeutic_Use_For |
Treatment of traveler's diarrhea |
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CAS_Registry |
6998-60-3 |
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CHEBI_ID |
CHEBI:26580 |
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Chemical_Formula |
C37H47NO12 |
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code |
C29406 |
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Contributing_Source |
FDA |
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definition |
A natural antibiotic produced by Streptomyces mediterranei, Rifamycin (Ansamycin Family) is a commonly used antimycobacterial drug that inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis; it blocks RNA-polymerase transcription initiation. Rifamycin has an activity spectrum against Gram-positive and Gram-negative bacteria, but is mainly used against Mycobacterium sp. (especially M. tuberculosis) in association with other agents to overcome resistance. (NCI04) |
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FDA_UNII_Code |
DU69T8ZZPA |
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Has_Salt_Form | ||
in_subset | ||
label |
Rifamycin |
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Legacy Concept Name |
Rifamycin |
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NCI_META_CUI |
CL560681 |
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NSC Number |
133100 145604 |
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Preferred_Name |
Rifamycin |
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prefixIRI |
NCIT:C29406 |
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prefLabel |
Rifamycin |
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Semantic_Type |
Pharmacologic Substance |
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subClassOf |