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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C29395
http://purl.obolibrary.org/obo/NCIT_C29395
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|---|---|
| Preferred Name | Pyrazinamide |
| Definitions |
A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04) |
|---|---|
| prefLabel | Pyrazinamide
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| label | Pyrazinamide
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| CHEBI_ID | CHEBI:45285
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| PDQ_Closed_Trial_Search_ID | 701809
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| code | C29395
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| prefixIRI | NCIT:C29395
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| in_subset | |
| Preferred_Name | Pyrazinamide
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| FDA_UNII_Code | 2KNI5N06TI
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| Contributing_Source | FDA
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| Chemical_Formula | C5H5N3O
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| Maps_To | Pyrazinamide
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| CAS_Registry | 98-96-4
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| NSC Number | 14911
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| NCI_Drug_Dictionary_ID | 701809
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| Legacy Concept Name | Pyrazinamide
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 701809
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0034239
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